OmegaXL Review 2025: Can This Joint and Muscle Support Supplement Truly Relieve Your Pain?
Can OmegaXL truly ease joint pain and support muscle function? Our in-depth review covers ingredients, customer feedback, and how it compares to other joint supplements.
Fact Checked
OmegaXL is a joint support supplement made with green-lipped mussel oil, olive oil, and vitamin E. The brand claims it can reduce inflammation, ease joint pain, and support muscle function—without using drugs or common fish oils.
But does OmegaXL actually work? Is it more effective than regular fish oil? Does it have any hidden drawbacks? And what are real customers saying about OmegaXL in unsponsored reviews?
In this guide, we’ll answer all of these questions and more. We’ll break down the ingredients, share what research says, showcase real customer experiences, and compare OmegaXL’s value to other best joint supplements.
By the end, you’ll know if this product is worth your money—or if there’s a better option.
Ingredient Analysis—Green-Lipped Mussel Oil Extract
Ingredient
Green-lipped mussel oil extract is often used in supplements for joint support due to its anti-inflammatory properties. It contains a mix of omega-3 fatty acids, including EPA, DHA, and ETA, that may help reduce joint pain and stiffness, especially in people with osteoarthritis.
Some studies suggest it can support joint comfort over time when taken consistently. In fact, a systematic review of nine clinical trials found that green-lipped mussel (GSM) extracts offer moderate and clinically meaningful pain relief for osteoarthritis (OA). While the results are promising, more high-quality research is needed to confirm effectiveness and determine the best form of GSM. Still, it may be a useful alternative for those looking to manage OA pain with fewer side effects.
Also, Omega XL delivers only 20.8 mg of EPA and 13.6 mg of DHA per serving. These amounts are significantly lower than those in standard fish oil supplements, which often provide several hundred milligrams per dose.
So, the low EPA and DHA content raises questions about its strength and overall effectiveness for inflammation relief.
Ingredient Analysis—Oil Extract (PCSO-524®)
OmegaXL’s also contains PCSO-524®, a patented lipid extract from New Zealand green-lipped mussels. It’s included in the brand’s 300 mg proprietary blend, along with olive oil and vitamin E. This blend is designed to support joint health and reduce inflammation—but does it really deliver?
A study published in the Journal of Marine Drugs compared PCSO-524® to standard fish oil. The results showed that patients using PCSO-524® experienced an 89% reduction in joint pain and 91% improvement in quality of life. So yes, the research does show it can help relieve joint discomfort.
But here’s the issue: OmegaXL doesn’t tell us how much PCSO-524® is actually inside each serving. The label just lists a 300 mg blend for everything combined. Without a specific dose for the extract, it’s hard to know if you’re getting enough to match the benefits seen in clinical studies.
And while PCSO-524® has promise, OmegaXL doesn’t include other research-backed joint ingredients—like glucosamine, chondroitin, turmeric, MSM, or Boswellia—which are commonly used in joint formulas like the one found in JointXL Plus. For a product focused on joint relief, that feels like a missed opportunity.
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So yes, the extract may help. But without proper dosing or supporting ingredients, this blend falls short.
We do not approve of this blend.
We Tried OmegaXL
OmegaXL
After hearing about OmegaXL’s claims to reduce inflammation, support joint health, and possibly aid in recovery, I decided to try it. Taking it daily was easy since the soft gels were small and easy to swallow. There was no aftertaste, which was a plus.
During the first month, I did notice a slight improvement in joint stiffness, especially after workouts. My knees felt less achy, and I could move around more comfortably. But there wasn't much difference in appetite control or a noticeable boost in energy. I also didn’t experience any changes in my weight or metabolism.
By the second month, the mild relief for joint discomfort continued, but there was no improvement in my energy levels or any noticeable effect on my weight. The convenience of taking OmegaXL was a positive. Still, beyond that, it didn’t seem to deliver the kind of results I was hoping for in terms of fat loss or metabolism.
In conclusion, while OmegaXL may relieve joint discomfort and aid muscle recovery, it doesn’t seem to offer much regarding weight loss or boosting energy levels. Given my experience, I wouldn’t consider it the most effective option for weight management. I’d rate it a 5/10 and not repurchase it for that reason.
During our research on OmegaXL, we found a YouTube video by ScamFinder, a trusted source for health-related insights.
Side Effects & Safety of OmegaXL
OmegaXL is considered safe by users, but individual reactions can vary. Since it contains green-lipped mussel oil extract, people with shellfish allergies should be cautious. Although the company claims to remove allergenic proteins during extraction, those with allergies should consult a healthcare provider before using OmegaXL.
Gastrointestinal discomfort, such as nausea, burping, or diarrhea, has been reported in some cases, similar to side effects experienced with other fish or marine oil supplements. These effects are usually mild but can be bothersome for sensitive users.
Pregnant and nursing women are advised to avoid OmegaXL, as animal studies suggest that green-lipped mussel extract may interfere with fetal development. People taking blood thinners or those with underlying medical conditions should also speak with their doctor before adding OmegaXL to their routine.
Real Customer Reviews
OmegaXL is a joint health supplement that some people are trying out to see if it can ease their joint pain and improve mobility. On Amazon, it has an average rating of 4.2 out of 5 stars, based on over 33,000 reviews.
A top positive review comes from Davis, who gave the product a 5/5 rating: We started buying this product a couple years back to help my mom with her mobility issues. Her ankles were swollen and her joints were very painful. At 83, she is now going for daily walks in the neighborhood and does not experience the pain she used to. It is expensive but it’s totally worth it.
A top negative review comes from Tammy, who rated OmegaXL 1/5 stars: This product has been heavily advertised to help reduce inflammation and joint pain... However, it did start a flatuence (passing gas) problem for me, something I did not have before taking OmegaXL, and it did cause my eyes to dry out terribly and did not help with pain or inflammation reduction... I stopped taking it because of the dry eye symptoms that returned.
Outside Amazon, OmegaXL has a lower presence on Trustpilot, where it holds a 2-star rating. The company is rated A+ by the Better Business Bureau (BBB), which shows that it responds to complaints and inquiries. However, 75 total complaints have been received in the past three years, most related to billing and refunds.
In summary, OmegaXL appears to work well for some users, especially for easing long-term joint discomfort. However, others have reported mild side effects and were disappointed with the results. The price point and return policies may also be a concern for some customers.
Where to Find the Best Value
OmegaXL is available for purchase on Amazon and the official Great HealthWorks website. Both platforms offer competitive pricing, but Amazon provides occasional discounts and subscription options that can help reduce the cost.From the official website:
- Two bottles (120 capsules) for the first order – $39.95
- Two bottles (120 capsules) for subsequent orders – $69.98 ($1.33 to $2.33 per day depending on dosage)
From Amazon:
- 60 soft gels (1 bottle) costs – $39.19 (discounted from $48.99)
- 30 servings (1 bottle) costs – $38.49
- Subscription option available with 20% off
Compared to other joint pain relief supplements that cost between $30 and $60 per month, OmegaXL is relatively more expensive.
If joint and muscle support is your goal, the price may be worth it. However, similar supplements may offer more affordable alternatives for those seeking weight loss or metabolism benefits.
Pros & Cons
Pros:
- Contains green-lipped mussel extract, which may help reduce inflammation.
- Small and easy-to-swallow soft gel capsules.
- No fishy aftertaste compared to regular fish oil supplements.
Cons
- Higher price compared to similar joint supplements.
- Contains very low amounts of DHA and EPA.
- Limited evidence supports its effectiveness for muscle and joint pain.
- It may not be suitable for individuals with shellfish allergies.
Should You Buy Omega XL?
People have different opinions about Omega XL. Some say it helps with joint pain and makes it easier to move, while others don’t feel much change even after using it for a while.
Most people don’t have side effects, but a few reported mild stomach problems like bloating or gas. And since Omega XL comes from green-lipped mussels, people with shellfish allergies should be careful.
The main ingredient, green-lipped mussel oil extract, helps reduce swelling and improve joint flexibility. It works well for many, but it may not be the best choice for serious joint pain.
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This is where JointXL Plus does better. It combines Glucosamine Sulfate, which helps protect joints, Chondroitin Sulfate, which keeps joints flexible, Turmeric, which helps reduce swelling, and MSM and boswellia serrata, both of which are known to reduce joint discomfort.
If you want stronger joint support, JointXL Plus may be a better choice. It uses these ingredients to help with pain, improve movement, and keep your joints healthy over time.
