Can You Take Prebiotics and Probiotics Together?

What Are Probiotics?

Probiotics are live bacteria, or cultures, that contribute to the overall health of our digestive systems. They can be consumed through certain foods or taken as dietary supplements.

The role of a probiotic is to help break down food in your gut and digestive system so your body can absorb the available nutrients and pass the rest of the food matter as waste.

Your body naturally makes some probiotic bacteria, but there are certain foods and supplements you can take to increase the amount of good bacteria in your gut and maintain good microbiota balance.

What Are Prebiotics?

The main difference between probiotics and prebiotics is that prebiotics aren’t actually live cultures of bacteria. Instead, what people are typically referring to when they mention prebiotics is dietary fiber.

The role of a prebiotic is to feed the good bacteria in your gut microbiota. So prebiotics don’t actually introduce live cultures of bacteria to your gut but create congenial conditions for healthy gut bacteria to thrive.

Essentially, prebiotics fuel the probiotic effect in your gut and exist mainly as a “food” or “fuel” source for actual probiotic bacteria. Like probiotics though, prebiotics can be consumed as natural food or in supplement form.

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Prebiotics and Probiotics Together?

To recap, prebiotics and probiotics have a symbiotic relationship. In fact, there is even a name given to the act of taking prebiotics and probiotics together: microbiome therapy.

The short answer to whether you can take prebiotics and probiotics together is yes. Taking these substances in conjunction with one another has been found to be safe and in many cases, more effective than simply taking a probiotic alone.

That’s because probiotics and prebiotics complement each other. Probiotics work to introduce live, beneficial bacteria cultures to your gut and prebiotics feed that good bacteria so it can do its job properly.

In fact, some supplements combine prebiotics and probiotics. These kinds of supplements are called synbiotics. Plenty of scientific evidence supports the idea that taking synbiotic supplements is beneficial for health in certain ways.

Benefits of Taking Prebiotics and Probiotics Together

Benefits of Taking Prebiotics and Probiotics Together

So why should you take prebiotics and probiotics together? Here are some scientifically valid reasons why such a practice could be beneficial for your health:

• Improved Digestion - Of course, the main goal for any prebiotic or probiotic supplement is to facilitate healthy digestion. Probiotics ensure that your gut has enough good bacteria to properly break down foods and absorb nutrients, while prebiotics fortify and support the functions of prebiotics. Probiotics help bloating by balancing gut bacteria and improving digestion, leading to reduced discomfort.
• Immune Support - The National Institutes of Health along with other leading research organizations have attested to the important role that probiotics and prebiotics play in supporting healthy immune response. The NIH has stated that, “Probiotic bacteria can interact and stimulate intestinal immune cells and commensal microflora to modulate specific immune functions..”
• Cognitive Benefits - Probiotics have also been found to benefit mental flexibility and alleviate stress in some studies. These studies indicate that probiotics can help strengthen the gut-brain axis and help prevent inflammation that can inhibit cognitive performance and exacerbate stress and anxiety.
• Athletic Performance - There have also been studies that suggest that taking a probiotic/prebiotic combination could help improve athletic performance. The method of action is still a topic of some debate but it could have something to do with allowing the body to absorb more nutrients from the foods you eat.

When to Take Prebiotics and Probiotics for Best Results

Good news for people who are interested in taking prebiotics and probiotics: there isn’t a strict rule about taking them at exactly the same time. Most research indicates that there is no immediate benefit to taking these substances at the same time. Still, you should take ingest a prebiotic and probiotic source at least once a day for the best results.

According to, Dr. Robynne Chutkan, Gastroenterologist

Probiotics and prebiotics are two sides of the same coin when it comes to gut health. While probiotics introduce beneficial bacteria to your gut, prebiotics provide the food those bacteria need to thrive. Together, they create a symbiotic relationship that supports digestion, boosts immunity, and may even contribute to better mental health. Incorporating both into your diet is a simple yet powerful way to nurture your microbiome and improve overall well-being.

Prebiotics can be taken pretty much any time of day while it is best to take probiotics (either as a supplement or as a food source) on an empty stomach, about 2-3 hours before or after a meal.

Result times can vary but most people who are consistent with taking prebiotics and probiotics daily notice changes after about a week or so.

Side Effects of Taking Prebiotics and Probiotics?

Health authorities consider prebiotic and probiotic consumption generally safe. If you are trying a probiotic regimen for the first time though, you may experience minor side effects such as:

• More gas than usual
• Loose stool
• Bloating
• Constipation
• Changes in appetite
• Acid reflux

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Prebiotic and Probiotic Supplements vs. Foods

The main difference between getting your probiotics and prebiotics through the food you eat as opposed to a supplement is that a supplement allows you to control the exact amount and type of bacteria you are introducing to your gut. Eating probiotic foods can be a bit more of a crap shoot.

On the other hand, supplements may not contribute to a balanced diet the way that probiotic foods can. Some probiotic foods include: For additional nutritional support, consider adding the best greens powder to your diet. It can provide essential vitamins and minerals while complementing the benefits of probiotics and prebiotics.

• Kefir
• Kombucha
• Sauerkraut
• Tempeh
• Pickles
• Kimchi

Both probiotic supplements and food have their ups and downs. Let’s take a look at the pros and cons of probiotic supplements specifically: